evaluation of nanosilver solution stability against streptococcus mutans, staphylococcus aureus and pseudomonas aeruginosa

نویسندگان

mohammad niakan department of microbiology, medicine faculty shahed university, tehran, ir iran; department of microbiology, medicine faculty shahed university, tehran, ir iran. tel: 9821-88964792, fax: 9821-88966310

hamid reza azimi department of oral and maxillofacial surgery, dentistry faculty, shahed university, tehran, ir iran

zahra jafarian dentistry faculty, shahed university, tehran, ir iran

golnoosh mohammadtaghi dentistry faculty, shahed university, tehran, ir iran

چکیده

objectives the aim of this study was to evaluate the stability of antibacterial properties of nanosilver solution during a period of 9 months against streptococcus mutans, staphylococcus aureus and pseudomonas aeruginosa. materials and methods in this in vitro study, the antibacterial effect of serial concentrations of nanosilver solution and amoxicillin antibiotic as control group on the standard bacteria s. mutans, s. aureus and p. aeruginosa were measured in 0-3-6-9 month period by disc diffusion methods. results the antibacterial activity and stability of nanosilver solution in comparison with amoxicillin antibiotic were measured and the results were examined by t-test statistical analysis. during 9 months, no significant changes were seen in antibacterial activity of nanosilver solution (4000 µg.ml-1), except for s. mutans. in other concentrations of nanosilver solution and amoxicillin, reduction of antibacterial activity was observed. conclusions antibacterial activity of 4000 µg.ml-1 nanosilver was stable in a 9 month duration but reduction of antibacterial activity in lower nanosilver concentrations and amoxicillin were significant in the same time period. background nanosilver compounds are admired in different fields of medicine and industry, due to their unique antibacterial properties. maximum contact of silver particles in nanosilver suspension causes increasing antibacterial effect of this compound.

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عنوان ژورنال:
jundishapur journal of microbiology

جلد ۶، شماره ۶، صفحات ۰-۰

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